Projects by JI Program

Cancer and Precision Health

Role of Exosome Signaling in Cancer Cell Dedifferentiation and Chemo-Resistance

Max Wicha, MD

Ming Luo, PhD

Wei Wei, MD

Decipher Immune Signatures and Therapeutic Response in Chinese and American Multiple Myeloma Patients

Christine Ye, MD

Xiao-Jun Huang, MD

The role of endoplasmic reticulum associated degradation (ERAD) in antigen presentation and immune evasion of multiple myeloma cells

Qing Li, MD, PhD

Yujun Dong, MD

Molecular signatures underlying the progression of intestinal meaplasia: a multi-omics approach

Andrea Tosisco, MD

John Kao, MD

Wen-Qing Li, PhD

Michigan-Peking Cancer Biomarker Collaborative

Arul Chinnaiyan, MD, PhD

Yuxin Yin, MD, PhD

New Strategy to Identify, Validate, and Eliminate Heterogeneity for Personalized Cancer Therapy of Breast Cancer or Liver Cancer

Duxin Sun, PhD

Ning Zhang, PhD

Cardiovascular Disease

Metabolic and epigenetic regulation in cell based heart repair

Zhong Wang, PhD

Ming Cui, MD, PhD

EMERALD-HF: Evaluation of MinERalocorticoid antagonists in ALdehyde dehydrogenase type 2 Deficiency

Bertram Pitt, MD

Porama Thanaporn, MD

Wei Gao, MD

β-adrenergic Receptor in Cardiac Injury and Atherosclerotic Plaque Stability: Role of NADPH Oxidase 4 (NOX4)

Marschall S. Runge, MD, PhD

Youyi Zhang, MD, PhD

Evaluation of SpironolactoNe versus Indapamide On Target Organ Damage in Patients with Obesity and hYpertension (ENVOY)

Bertram Pitt, MD

Guisong Wang, MD

Overcoming Racial and Metabolic Heterogeneity in Antiplatelet Therapy

Daniel Eitzman, MD, PhD

Haoming Zhang, PhD

Jianping Li, MD, PhD

Multi-ethnic Study of Genetic Risk Factors to Discover Mechanisms of Aortic Aneurysm and Dissection

Cristen Willer, PhD

Zhe Zhang, MD

A Chemical approach to Generating Patient-specific Cardiac Stem Cells for Cell Therapy against Cardiovascular Disease

Zhong Wang, PhD

Hongkui Deng, MD

The Role of Hematopoietic Factors in Atherosclerotic Vascular Diseases

Santhi Ganesh, MD

Yan Zhang, MD

Molecular Mechanisms of Fibrosis and the Progression from Paroxysmal to Persistent Atrial Fibrillation

Jose Jalife, MD, PhD

Xuebin Li, MD

Identify Smooth Muscle Cell Specific Protein as Biomarkers for Early Diagnosis of Acute Aortic Dissection

Bo Yang, MD

Zhe Zhang, MD

Quantitative Measurements of Brain Iron Overload after Intracerebral Hemorrhage

Guohua Xi, MD

Yining Huang, MD

Particulate Matter Air Pollution and High Density Lipoprotein Dysfunction

Robert Brook, MD

Jianping Li, MD, PhD

Blood Pressure and Hypertension Genetics

Santhi Ganesh, MD

Yan Zhang, MD

Dysfunctional HDL and Cardiovascular Disease

Eugene Chen, MD

Guisong Wang, MD

Finding Genes for Myocardial Infarction and Blood Lipid Levels in a Chinese Sample from Beijing

Cristen Willer, PhD

Ming Xu, PhD

Exploratory

Nanobubble water combined with apyrase as root canal irrigant inhibits biofilm and virulence of Enterococcus faecalis

Chuanwu Xi, PhD

Yanmei Dong, DDS, PhD

Clinical Validation of a Patient-specific Pharmacogenomics Assay for Enhanced Treatment Response in Bipolar Disorder-1 (BPD-1) Patients

Brian Athey, PhD

Lin Lu, MD, PhD

Optimization of Limb Salvage Strategy for Critical Limb Ischemia Using Quantitative Vascular Imaging Biomarkers

J. Brian Fowlkes, PhD

Xiaofeng Yin, MD, PhD

Assessing Genomic and Environmental Drivers of Depression in Training Physicians across China and the US

Srijan Sen, MD, PhD

Hongqiang Sun, MD, PhD

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