JI Team Publications

2021

Improved diagnostic prediction of the pathogenicity bloodstream isolates of Staphylococcus epidermidis
PLoS One
U-M PI: J. Scott Van Epps

 

Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy
Kidney International
U-M PI: Wenjun Ju & Matthias Kretzler
PKUHSC PI: Min Chen

 

The Prevalence of Diabetic Microvascular Complications in China and the United States
Current Diabetes Reports
U-M PI: Rodica Busui
PKUHSC PI: Luxia Zhang

 

Associations of Genetic Variants Contributing to Gut Microbiota Composition in Immunoglobin A Nephropathy
mSystems
PKUHSC PI: Hong Zhang

 

Potential Roles of Oral Microbiota in the Pathogenesis of Immunoglobin A Nephropathy
Frontiers in Cellular and Infection Microbiology
PKUHSC PI: Hong Zhang

 

Five Novel Loci Are Implicated in Predisposing to IgA Nephropathy by an Exome-Wide Association Study of Han Chinese
Clinical Journal of the American Society of Nephrology
U-M PI: Christine Berthier
PKUHSC PI: Hong Zhang

 

Reverse Microbiomics: a new reverse dysbiosis analysis strategy and its usage in prediction of autoantigens and virulent factors in dysbiotic gut microbiomes from rheumatoid arthritis patients
Frontiers in Microbiology
U-M PI: Oliver He

 

PINA 3.0: mining cancer interactome
Nucleic Acids Research
PKUHSC PI: Jianmin Wu

 

Disclosure of clinically actionable genetic variants to thoracic aortic dissection biobank participants
BMC Medical Genomics
U-M PI: Cristen Willer

 

Ethical Perspectives of Chinese and United States Physicians within a Research Collaborative
Accountability in Research
U-M PIs: Michael Geisser, Joseph Kolars, & Raymond Hutchinson
PKUHSC PI: Yali Cong

 

Advancing science and education through a novel collaboration platform between the University of Michigan and Peking University Health Science Center
FASEB BioAdvances
U-M PI: Joseph Kolars
PKUHSC PI: Qimin Zhan

 

Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders
Blood
U-M PI: Yongqing Li

 

Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection
Scientific Data
U-M PI: Oliver He

 

2020

Albuminuria and retinal vessel density in diabetes without diabetic retinopathy: the Kailuan Eye Study. Acta Ophthalmol. 2020.
Acta Ophthalmolgica
PKUHSC PI: Luxia Zhang

 

Immunoproteasome in IgA Nephropathy: State-of-Art and Future Perspectives
International Journal of Biological Sciences
PKUHSC PI: Hong Zhang

 

Perspectives on how mucosal immune responses, infections, and gut microbiome shape IgA nephropathy, and future therapies
Theranostics
PKUHSC PI: Hong Zhang

 

CVCDAP: an integrated platform for molecular and clinical analysis of cancer virtual cohorts
Nucleic Acids Research
PKUHSC PI: Jianmin Wu

 

Non-thermal histotripsy tumor ablation promotes abscopal immune responses that enhance cancer immunotherapy
Journal for Immunotherapy of Cancer
U-M PI: Clifford Cho

 

Aortic progression and reintervention in patients with pathogenic variants after a thoracic aortic dissection
Journal of Thoracic and Cardiovascular Surgery
U-M PI: Cristen Willer

 

Soluble urokinase-type plasminogen activator receptor and incident end-stage renal disease in Chinese patients with chronic kidney disease
Nephrology Dialysis Transplantation
PKUHSC PI: Minghui Zhao

 

Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis
JCI Insight
U-M PIs: Yongqing Li & Hasan Alam

 

Associations of Urinary Epidermal Growth Factor and Monocyte Chemotactic Protein-1 with Kidney Involvement in Patients with Diabetic Kidney Disease
Nephrology Dialysis Transplantation
PKUHSC PIs: Min Chen, Minghui Zhao & Luxia Zhang

 

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
Science
U-M PIs: Yongqing Li & Hasan Alam

 

PAD2 Mediates Caspase-1 Associated Lethality in Pseudomonas Aeruginosa Pneumonia Induced Sepsis
Journal of Infectious Disease
U-M PIs: Yongqing Li & Hasan Alam

 

Inhibition of PAD2 Improves Survival in a Mouse Model of Lethal LPS-Induced Endotoxic Shock
Inflammation
U-M PIs: Yongqing Li & Hasan Alam

 

Hemoglobin and erythrocyte count are independently and positively associated with arterial stiffness in a community-based study
Journal of Human Hypertension
U-M PI: Santhi Ganesh
PKUHSC PI: Yan Zhang

 

Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678
Arteriosclerosis, Thrombosis, and Vascular Biology
U-M PIs: Daniel Eitzman, Haoming Zhang & Eugene Chen
PKUHSC PI: Jianping Li

 

2019

Podocytes and autophagy: A potential therapeutic target in lupus nephritis
Autophagy
PKUHSC PI: Hong Zhang

 

Autophagy and immunological aberrations in systemic lupus erythematosus
European Journal of Immunology
PKUHSC PI: Hong Zhang

 

Disruption of Histidine and Energy Homeostasis in Chronic Obstructive Pulmonary Disease
International Journal of Chronic Obstructive Pulmonary Disease
U-M PI: Theodore Standiford
PKUHSC PI: Bei He

 

Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study
Scientific Reports
U-M PI: Theodore Standiford
PKUHSC PI: Bei He

 

Training Pathways to Working as a General Practitioner in China
Family Medicine
U-M PI: Michael Fetters

 

Survey of Nonalcoholic Fatty Liver Disease Knowledge, Nutrition, and Physical Activity Patterns Among the General Public in Beijing, China
Digestive Diseases and Sciences
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Awareness and Knowledge of Nonalcoholic Fatty Liver Disease Among Office Employees in Beijing, China
Digestive Diseases and Sciences
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Accumulation, Liver Fibrosis, and Metabolic Abnormalities in Chinese Patients With Moderate/Severe Versus Mild Hepatic Steatosis
Hepatology Communication
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Sorafenib Encapsulated in Nanocarrier Functionalized With glypican-3 Specific Peptide for Targeted Therapy of Hepatocellular Carcinoma
Colloids and Surfaces B: Biointerfaces
U-M PI: Thomas Wang
PKUHSC PI: Jiye Zhu

 

Peptidylarginine Deiminase 2 Knockout Improves Survival in Hemorrhagic Shock
Shock
U-M PIs: Hasan Alam, Yongqing Li & Thomas Wang
PKUHSC PIs: Tianbing Wang & Baoguo Jiang

 

OHMI: the ontology of host-microbiome interactions
Journal of Biomedical Semantics
U-M PI: Oliver He
PKUHSC PI: Jianmin Wu

 

Increased mitochondrial NADPH oxidase 4 (NOX4) expression in aging is a causative factor in aortic stiffening
Redox Biology
U-M PI: Marschall Runge
PKUHSC PI: You Yi Zhang

 

Clinical Implications of Identifying Pathogenic Variants in Individuals With Thoracic Aortic Dissection
Circulation: Genomic and Precision Medicine
U-M PI: Cristen Willer

 

HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarction.
EBioMedicine
U-M PIs: Zhong Wang, Hasan Alam, Yongqing Li & Eugene Chen

 

Effects of medication-assisted treatment on mortality among opioids users: a systematic review and meta-analysis
Molecular Psychiatry
U-M PIs: Fred Blow & Mark Ilgen
PKUHSC PI: Lin Lu

 

The rising crisis of illicit fentanyl use, overdose, and potential therapeutic strategies
Translational Psychiatry
PKUHSC PI: Lin Lu

 

2018

Profile of psychiatric symptoms in methamphetamine users in China: Greater risk of psychiatric symptoms with a longer duration of use
Psychiatry Research
PKUHSC PI: Lin Lu

 

Epidemiological characteristics and risk factors of methamphetamine-associated psychotic symptoms
Frontiers in Psychiatry
PKUHSC PI: Lin Lu

 

Poly-drug use of prescription medicine among people with opioid use disorder in China: A systematic review and meta-analysis
Substance Use and Misuse
PKUHSC PI: Lin Lu

 

Serum uromodulin and progression of kidney disease in patients with chronic kidney disease
Journal of Translational Medicine
PKUHSC PI: Minghui Zhao

 

Increased autophagy is cytoprotective against podocyte injury induced by antibody and interferon-alpha in lupus nephritis
Annals of the Rheumatic Diseases
PKUHSC PI: Hong Zhang

 

Exploring the Role of Autophagy-Related Gene 5 (ATG5) Yields Important Insights Into Autophagy in Autoimmune/Autoinflammatory Diseases
Frontiers in Immunology
PKUHSC PI: Hong Zhang

 

Mortality risk of chronic kidney disease: A comparison between the adult populations in urban China and the United States
PLoS One
U-M PI: Jennifer Bragg-Gresham

 

Prevalence and Risk Factors for CKD: A Comparison Between the Adult Populations in China and the United States.
Kidney International Reports
U-M PI: Jennifer Bragg-Gresham
PKUHSC PI: Ming-hui Zhao

 

Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders
Toxicology In Vitro
U-M PI: Steven Huang
PKUHSC PI: Yahong Chen

 

Multiregional sequencing reveal genomic alterations and clonal dynamics in primary malignant melanoma of the esophagus
Cancer Research
U-M PI: Jun Li
PKUHSC PI: Yang Ke

 

Inhibition of Peptidylarginine Deiminase Alleviates LPS-induced Pulmonary Dysfunction and Improves Survival in a Mouse Model of Lethal Endotoxemia
European Journal of Pharmacology
U-M PIs: Hasan Alam & Yongqing Li

 

Relationship between the duration of methamphetamine use and psychotic symptoms: A two-year prospective cohort study
Drug and Alcohol Dependence
U-M PI: Fred Blow

 

Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease
PLoS One
U-M PI: Eugene Chen
PKUHSC PI: Guisong Wang

 

Effect of Ambient Fine Particulate Matter Air Pollution and Colder Outdoor Temperatures on High-Density Lipoprotein Function
American Journal of Cardiology
U-M PI: Robert Brook

 

Short-Term Blood Pressure Responses to Ambient Fine Particulate Matter Exposures at the Extremes of Global Air Pollution Concentrations
American Journal of Hypertension
U-M PI: Robert Brook
PKUHSC PI: Jianping Li

 

Structural basis for the antiarrhythmic blockade of a potassium channel with a small molecule
FASEB Journal
U-M PI: Jose Jalife

 

Minocycline effects on intracerebral hemorrhage-induced iron overload in aged rats: brain iron quantification with MRI
Stroke
U-M PI: Guohua Xi

 

Early Hemolysis Within Human Intracerebral Hematomas: an MRI Study
Translational Stroke Research
U-M PI: Guohua Xi

 

Urinary Epidermal Growth Factor Predicts Renal Prognosis in Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Annals of Rheumatic Diseases
U-M PI: Wenjun Ju
PKUHSC PI: Ming-hui Zhao

 

2017

Pattern and related factors of cognitive impairment among chronic methamphetamine users
American Journal of Addiction
PKUHSC PI: Lin Lu

 

Chinese herbal medicine for the treatment of drug addiction
International Review of Neurobiology
PKUHSC PI: Lin Lu

 

Accelerated podocyte detachment and progressive podocyte loss from glomeruli with age in Alport Syndrome
Kidney International
U-M PI: Roger Wiggins
PKUHSC PI: Jie Ding

 

Collaboration platforms in China for translational and clinical research: the partnership between Peking University Health Science Center and the University of Michigan Medical School
Academic Medicine
U-M PI: Joseph Kolars
PKUHSC PI: Weigang Fang

 

Education Improves Patient Knowledge and Acceptance on Antiviral Therapy of Hepatitis C in Rural China
Chinese Medical Journal
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Risk Assessment of Hepatocellular Carcinoma in Patients with Hepatitis C in China and the USA
Digestive Disease and Sciences
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Temporal changes in the modes of hepatitis C virus transmission in the USA and Northern China
Digestive Disease and Sciences
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Mutation landscape and intratumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing
Oncotarget
U-M PI: Jun Li
PKUHSC PI: Yang Ke

 

The higher prevalence of truncal obesity and diabetes in American than Chinese patients with chronic hepatitis C might contribute to more rapid progression to advanced liver disease
Alimentary Pharmacology & Therapeutics
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock
Scientific Reports
U-M PI: Hasan Alam
PKUHSC PI: Baoguo Jiang

 

Personal-level exposure to environmental temperature is a superior predictor of edothelialdpendent vasodilatation than outdoor-ambient level
Journal of the American Society of Hypertension
U-M PI: Robert Brook
PKUHSC PI: Jianping Li

 

Transplantation of multipotent Isl1+ cardiac progenitor cells preserves infarcted heart function in mice
American Journal of Translational Research
U-M PI: Zhong Wang
PKUHSC PI: Hongkuei Deng

 

Air Pollution and Cardiometabolic Disease: An Update and Call for Clinical Trials
American Journal of Hypertension
U-M PI: Robert Brook
PKUHSC PI: Jianping Li

 

Transplantation of Isl1+ Cardiac Progenitor Cells in Small Intestinal Submucosa Improves Infarcted Heart Function
Stem Cell Research Therapy
U-M PI: Zhong Wang

 

CD163 expression in neurons after experimental intracerebral hemorrhage
Stroke
U-M PI: Guohua Xi
PKUHSC PI: Yining Huang

 

Eplerenone Reduces Atrial, Fibrillation Burden Without Preventing Atrial Electrical Remodeling
Journal of the American College of Cardiology
U-M PI: Jose Jalife

 

“Stressed” About Air Pollution: Time for Personal Action
Circulation
U-M PI: Robert Brook
PKUHSC PI: Jianping Li

 

Exome chip meta-analysis identifies novel loci and East Asian–specific coding variants contributing to lipid levels and coronary artery disease
Nature Genetics
U-M PI: Christen Willer
PKUHSC PI: Ming-Hsu

 

Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency
Cell
U-M PI: Zhong Wang
PKUHSC PI: Hongkuei Deng

 

2016

In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft
Photoacoustics
U-M PI: Thomas Wang
PKUHSC PI: Jiye Zhu

 

A Comparative Study of Liver Disease Care in the USA and Urban and Rural China
Digestive Disease and Sciences
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

In vivo fluorescence imaging of hepatocellular carcinoma xenograft using near-infrared labeled epidermal growth factor receptor (EGFR)
Biomedical Optic Express
U-M PI: Thomas Wang
PKUHSC PI: Jiye Zhu

 

Survey of hepatitis B knowledge and stigma among chronically infected patients and uninfected persons in Beijing, China.
Liver International
U-M PI: Anna Lok
PKUHSC PI: Lai Wei

 

Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
Scientific Reports
U-M PI: Hasan Alam
PKUHSC PI: Baoguo Jiang

 

Quantitative analysis of MR imaging to assess treatment response for patients with multiple myeloma by using dynamic intensity entropy transformation: a preliminary study
Radiology
U-M PI: Qian Dong
PKUHSC PI: Jin Lu

 

Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes. JACC: Basic to Translational Science
JACC: Basic to Translational Science
U-M PI: Jose Jalife

 

Improving cardiac reprogramming for heart regeneration
Current Opinion in Organ Transplantation
U-M PI: Zhong Wang
PKUHSC PI: Hongkuei Deng

 

Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts
Cell Discovery
U-M PI: Zhong Wang
PKUHSC PI: Hongkuei Deng

 

Atrial Fibrillation Susceptibility in Obesity: An Excess Adiposity and Fibrosis Complicity?
Circulation Research
U-M PI: Jose Jalife

 

Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
Nature Genetics
U-M PI: Santhi Ganesh
PKUHSC PI: Yan Zhang 2016

 

2015

NEPTUNE and PKU-IgAN Consortium (2015) Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker
Science Translational Medicine
U-M PI: Mattias Kretzler
PKUHSC PI: Minghuei Zhao