All Projects

2021

The role of endoplasmic reticulum associated degradation (ERAD) in antigen presentation and immune evasion of multiple myeloma cells

Qing Li, MD, PhD
Yujun Dong, MD

Malic Enzyme Dependence is a Therapeutic Vulnerability in Pancreatic and Gastric Cancers

Costas Lyssiotis, PhD
Shigang Ding, MD

Assessing Genomic and Environmental Drivers of Depression in Training Physicians across China and the US

Srijan Sen, MD, PhD
Hongqiang Sun, MD, PhD

Metabolic and epigenetic regulation in cell based heart repair

Zhong Wang, PhD
Ming Cui, MD, PhD

Role of Exosome Signaling in Cancer Cell Dedifferentiation and Chemo-Resistance 

Max Wicha, MD
Ming Luo, PhD
Wei Wei, MD

Nanobubble water combined with apyrase as root canal irrigant inhibits biofilm and virulence of Enterococcus faecalis 

Chuanwu Xi, PhD
Yanmei Dong, DDS, PhD

Decipher Immune Signatures and Therapeutic Response in Chinese and American Multiple Myeloma Patients

Christine Ye, MD
Xiao-Jun Huang, MD

Clinical Validation of a Patient-specific Pharmacogenomics Assay for Enhanced Treatment Response in Bipolar Disorder-1 (BPD-1) Patients

Brian Athey, PhD
Lin Lu, MD, PhD

Optimization of Limb Salvage Strategy for Critical Limb Ischemia Using Quantitative Vascular Imaging Biomarkers

J. Brian Fowlkes, PhD
Xiaofeng Yin, MD, PhD

Single Cell RNA Sequencing to identify transcriptional signatures of failure to repair after Acute Kidney Injury in patients with and without Covid‐19 disease

Matthias Kretzler, MD
Li Yang, MD

2019

Determining genetic and microbiome effects on non-alcoholic fatty liver disease and its medical complications in a Chinese population

Elizabeth Speliotes, MD, PhD, MPH
Linong Ji, MD

LILRA3 as a novel regulator of thrombioinflammation in antiphospholipid syndrome (APS)

Jason Knight, MD, PhD
Jianping Guo, MD, PhD

Molecular signatures underlying the progression of intestinal meaplasia: a multi-omics approach

Andrea Tosisco, MD
John Kao, MD
Wen-Qing Li, PhD

Gaining insight into retinal cell death: rational drug development through vitreous proteomic analysis

David Zacks, MD, PhD
Liu Yang, MD, PhD

Citrullinated Histone H3: A Mediator and Biomarker of Sepsis-induced Acute Lung Injury

Yongqing Li, MD, PhD
Tianbing Wang, MD

Michigan-Peking Cancer Biomarker Collaborative

Arul Chinnaiyan, MD, PhD
Yuxin Yin, MD, PhD

EMERALD-HF: Evaluation of MinERalocorticoid antagonists in ALdehyde dehydrogenase type 2 Deficiency

Bertram Pitt, MD
Porama Thanaporn, MD
Wei Gao, MD

New Strategy to Identify, Validate, and Eliminate Heterogeneity for Personalized Cancer Therapy of Breast Cancer or Liver Cancer

Duxin Sun, PhD
Ning Zhang, PhD

Deferoxamine in the Treatment of Aneurysmal Subarachnoid Hemmorrhage (DISH)

Aditya Pandey, MD
Yining Huang, MD

Building a Learning Health System for Kidney Disease through Meaningful Use of Electronic Health Record Data in Yinzhou China

Charles Friedman, PhD
Luxia Zhang, MD

2018

Understanding the Heterogeneity in the Risk for Diabetes Complications in China and U.S.

Rodica Busui, MD, PhD
Luxia Zhang, MD

Identification and Establishment of Novel Pathogenetic Genes Involved in Intellectual Disability/ Developmental Delay with Hypomeylinating Leukodystrophy in China

Margit Burmeister, PhD
Jingmin Wang, MD, PhD

Systemic Investigation of the Microbiome-host Interactions in H. pylori-associated Gastric Cancer Patients

Yongqun (Oliver) He, PhD
Jianmin Wu, PhD

Identification of Tumoricidal T Cell Receptors from Hepatocellular Carcinomainfiltrating CD8+ T Lymphocytes

Clifford Cho, MD, FACS
Yuan Hong, MD, PhD

Therapeutic Implications of Natural Killer Cell Immune Surveillance in Lung Cancer

Venkat Keshamouni, PhD
Jun Wang, MD, PhD

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